Epilepsy

Epilepsy Surgeries

The goal of epilepsy surgery may be to control seizures by resection of the epileptogenic lesion or region. In patients who are not candidates for cortical resection, surgery may be considered for palliation, as with disconnection procedures.
Canadian pharmacy
85% of partial epilepsies arise from the temporal lobe and therefore the most common resective procedure is the [...]


Epilepsy Surgery

Treating the Medically Intractable Patient
Canadian pharmacy
Patients who continue to have seizures despite treatment with appropriate AEDs in monotherapy over six months should be referred to a neurologist. If seizures are not controlled within six months, then referral to a tertiary epilepsy center is indicated. If it is established that seizures are epileptic, then the patient [...]


When to begin AEDs

Whether to begin an AED after a first seizure depends on the risks of further seizures, of seizure related injury, psychological distress, loss of employment and loss of driving privileges. Alternatively, the risk of adverse effects from exposure to AEDs must be considered, as well as the likelihood that medication will be effective. Since these [...]


While severe and even sometimes life threatening

While severe and even sometimes life threatening, idiosyncratic reactions are rare and unpredictable. Idiosyncratic reactions arise with every one of the older AEDs and with Felbamate, and include bone marrow suppression, allergic reactions and gastrointestinal effects.
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New AEDs are needed because existing agents are not completely efficacious or tolerated, especially for patients with [...]


Principles of Clinical Use of Antiepileptic Drugs

The goal of pharmacological treatment of epilepsy is to control seizures without adverse medication-related side effects. This goal is not always attained. While primary generalized epilepsies respond well to medication, 45% of patients with partial epilepsies continue to have seizures despite optimal medical management. These patients seek a balance between seizures and medication related side [...]


Epilepsy

Diagnosis of Seizures
The selection of a course of treatment and accurate prognostic counseling require correct diagnosis and classification of the epileptic seizure type. Seizures are classified as partial onset or generalized onset by ictal behavior and EEG. The most common diagnostic differential for the adult neurologist is determining whether a paroxysmal, stereotyped neurological event is [...]